Purposeful validation of sorted fractions was done by xenotransplantation, the results of which was coupled with miRNA expression profiling to deliver stem cell-relevant miRNA expression profiles. To ascertain whether or not miRNA are differentially expressed in LSC and HSC, we fractionated sixteen AML affected person samples and a few lineage-d

Functional validation of sorted fractions was executed by xenotransplantation, the results of which was coupled with miRNA expression profiling to generate stem cell-relevant miRNA expression profiles. To determine whether miRNA are differentially expressed in LSC and HSC, we fractionated 16 AML patient samples and 3 lineage-depleted (Lin–) wi

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